| Product Number |
OPCD00245 |
| Product Page |
www.avivasysbio.com/rab1a-recombinant-protein-opcd00245.html |
| Name |
RAB1A Recombinant Protein (OPCD00245) |
| Protein Size (# AA) |
Ser2~Cys205 amino acids |
| Molecular Weight |
26kDa |
| Tag |
N-terminal His Tag |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
5861 |
| Host |
E.coli |
| Purity |
>95% |
| Concentration |
200 ug/mL (prior to lyoph) |
| Source |
E.coli |
| Gene Full Name |
RAB1A, member RAS oncogene family |
| Alias Symbols |
GTP binding protein Rab1a;Rab GTPase YPT1 homolog;RAB1;RAB1, member RAS oncogene family;ras-related protein Rab-1A;YPT1;YPT1-related protein. |
| Product Format |
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
| Description of Target |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport. |
| Reconstitution and Storage |
2°C to 8°C|-80°C |
| Datasheets/Manuals |
Printable datasheet for RAB1A Recombinant Protein (OPCD00245) |
| Additional Information |
Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Isoelectric Point: 5.9
Subcellular Location: Golgi apparatus |
| Additional Information |
Residues: Ser2-Cys205 |
| Uniprot ID |
P62820 |
| Protein Name |
Ras-related protein Rab-1A |
| Protein Accession # |
NP_004152.1 |
| Nucleotide Accession # |
NM_004161.4 |
| Gene Symbol |
RAB1A |
| Predicted Species Reactivity |
Homo sapiens|Human |
| Application |
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
| Image 1 | SDS-PAGE
 | RAB1A Recombinant Protein (OPCD00245) using SDS-PAGE |
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