| Product Number |
OPCA03432 |
| Product Page |
www.avivasysbio.com/zp3-recombinant-protein-human-opca03432.html |
| Name |
ZP3 Recombinant Protein (Human) (OPCA03432) |
| Protein Size (# AA) |
Recombinant amino acids |
| Molecular Weight |
56.6 kDa |
| Tag |
N-terminal 6xHis-SUMO-tagged |
| NCBI Gene Id |
7784 |
| Host |
Human |
| Purity |
Greater than 90% as determined by SDS-PAGE. |
| Source |
E.coli |
| Gene Full Name |
zona pellucida glycoprotein 3 |
| Protein Range |
23-387 aa |
| Alias Symbols |
OOMD3;sperm receptor;Zona pellucida glycoprotein 3;zona pellucida glycoprotein 3B;zona pellucida glycoprotein ZP3;zona pellucida protein C;zona pellucida sperm-binding protein 3;Zp-3;ZP3A;ZP3A/ZP3B;ZP3B;ZPC. |
| Peptide Sequence |
QPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSV |
| Product Format |
Liquid or Lyophilized powder |
| Reference |
Cloning and characterization of the human sperm receptor ligand ZP3: evidence for a second polymorphic allele with a different frequency in the Caucasian and Japanese populations.van Duin M., Polman J.E., Verkoelen C.C., Bunschoten H., Meyerink J.H., Olijve W., Aitken R.J. Genomics 14:1064-1070(1992) |
| Description of Target |
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Reconstitution and Storage |
-20°C or -80°C |
| Protein Sequence |
QPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSV |
| Datasheets/Manuals |
Printable datasheet for ZP3 Recombinant Protein (Human) (OPCA03432) (OPCA03432) |
| Additional Information |
Relevance: The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Formulation |
20 mM Tris-HCl based buffer, pH 8.0 |
| Storage Buffer |
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Uniprot ID |
P21754 |
| Protein Name |
Zona pellucida sperm-binding protein 3 |
| Protein Accession # |
NP_001103824.1
|
| Nucleotide Accession # |
NM_001110354.1 |
| Gene Symbol |
ZP3 |
| Predicted Species Reactivity |
Homo sapiens|Human |
| Image 1 | Protein SDS-PAGE
 | ZP3 Recombinant Protein (Human) (OPCA03432) in SDS-PAGE showing the molecular weight of approximately 56.69 kDa. |
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