| Product Number |
OOPA00055 |
| Product Page |
www.avivasysbio.com/bd-1-antibody-oopa00055.html |
| Name |
BD 1 Protein (OOPA00055) |
| Protein Size (# AA) |
Recombinant amino acids |
| Host |
Escherichia Coli. |
| Purity |
Greater than 97.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE. |
| Alias Symbols |
Beta-defensin 1, BD-1, Defensin beta 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822. |
| Peptide Sequence |
DQYKCLQHGG FCLRSSCPSN TKLQGTCKPD KPNCCKS. |
| Product Format |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Reconstitution and Storage |
Lyophilized Mouse BD 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution BD 1 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OOPA00055 |
| Additional Information |
Solubility: It is recommended to Reconstitution: Reconstitute the lyophilized Mouse BD-1 in sterile 18M?-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions. |
| Formulation |
Lyophilized from a 0.2um filtered concentrated solution in PBS, pH7.4. |
| Biological Activity |
Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml. |
| Additional Information |
Product Introduction: The Defensin family are highly similar in their protein sequence and are microbicidal & cytotoxic peptides made by neutrophils. Beta Defensin-1 is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. Beta Defensin-1 has close proximity to Defensin Alpha-1 and has been implicated in the pathogenesis of cystic fibrosis. Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human Beta Defensin-1 mRNA expression and higher human Beta Defensin-2 and human Beta Defensin-3 mRNA expression. Beta Defensin is highly expressed by epithelial cells. Beta-defensin 1 may play a role in the pathogenesis of severe sepsis.
Product Description: BD 1 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 KDa. The BD 1 Mouse is purified by proprietary chromatographic techniques. |
| Purification |
Greater than 97.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE. |
| Gene Symbol |
BD 1 |
| Predicted Species Reactivity |
Mouse |
| Image 1 | |
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