proNT3 Protein (OOPA00031)

• Product Number: OOPA00031
• Name: proNT3 Protein (OOPA00031)
• Host: Escherichia Coli.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Alias Symbols: Precursor Form Neurotrophin-3, proNT-3.
• Peptide Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Asn-Asn-Met-Asp-Gln.
• Product Format: Sterile Filtered White lyophilized (freeze-dried) powder.
• Reconstitution and Storage: Lyophilized proNT3 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution proNT3 should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.
• Additional Information: Solubility: It is recommended to Reconstitution: Reconstitute the lyophilized proNT3 in sterile 18M?-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
• Formulation: proNT3 was lyophilized from a concentrated (1mg/ml) solution in 20mM PB, pH 8.0 and 300mM NaCl.
• Additional Information: Product Introduction: proNT-3 (the precursor form of neurotrophin-3) functions through p75NTR and sortilin and induces neuronal apoptosis. In contrast, mature NT-3 interacts with Trk receptors and selectively promotes the survival, growth and differentiation of neurons. Since axon retrograde transport is crucial for neurotrophin signaling, proNT-3 also has an important role in the mechanism of retrograde signaling.
  Product Description: proNT3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 239 amino acids and having a molecular mass of 27.4kDa. The proNT3 is purified by proprietary chromatographic techniques.
• Purification: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Gene Symbol: proNT3
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