IL2RA Antibody (OATA00537)

Data Sheet
 
Product Number OATA00537
Product Page www.avivasysbio.com/il2ra-antibody-oata00537.html
Name IL2RA Antibody (OATA00537)
Clone BC96
Isotype Mouse IgG1, kappa
Conjugation Unconjugated
NCBI Gene Id 3559
Host Mouse
Clonality Monoclonal
Gene Full Name interleukin 2 receptor subunit alpha
Alias Symbols p55, CD25, IL2R, IMD41, TCGFR, IDDM10
Product Format Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2
Reference

Willer DO, Ambagala APN, Pilon R, chan JK, Fournier J, Brooks J, Sandstrom P, and MacDonald KS. 2012. J. Virol. 86: 3626-3634. (Flow cytometry - cynomolgus)

Ruffell B, Au A, Rugo HS, Esserman LJ, Hwang ES, and Coussens LM. 2012. Proc. Natl. Acad. Sci. 109: 2796-2801. (Flow cytometry)

Mackroth MS, Malhotra I, Mungai P, Koech D, Muchiri E, and King CL. 2011. J. Immunol. 186: 2780-2791. (Flow cytometry)

Mori T, Miyamoto T, Yoshida H, Asakawa M, Kawasumi M, Kobayashi T, Morioka H, Chiba K, Toyama Y, and Yoshimura A. 2011. Int. Immunol. 23(11):701-712. (Cell sorting / negative selection - T cells)

Wan Q, Kozhaya L, ElHed A, Ramesh R, Carlson TJ, Djretic IM, Sundrud MS, and Unutmax D. 2011. J. Exp. Med. 208: 1875-1887. (Cell sorting / negative selection - T cells)

Verhoeven D, Sankaran S, Silvey M, and Dandekar S. 2008. J. Virol. 82: 4016-4027. (Flow cytometry - rhesus macaque)

Description of Target The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Reconstitution and Storage 2-8C
Datasheets/Manuals Printable datasheet for OATA00537
Specificity CD25
Application Info This purified format is guaranteed to be >90% pure as determined by SDS-PAGE analysis. Citations are provided as a convenience to you - please consult Materials and Methods sections for additional details about the use of any product in these publications.
Uniprot ID P01589
Protein Name interleukin-2 receptor subunit alpha
Protein Accession # NP_000408.1?
Nucleotide Accession # NM_000417.2
Tested Species Reactivity Human
Gene Symbol IL2RA
Predicted Species Reactivity Baboon, Chimpanzee, Cynomolgus, Rhesus
Application FC
Image 1

 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com