| Product Number |
OASG05678 |
| Product Page |
www.avivasysbio.com/park2-antibody-phospho-ser131-oasg05678.html |
| Name |
PARK2 Antibody (Phospho-Ser131) (OASG05678) |
| Molecular Weight |
55 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
5071; |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
parkin RBR E3 ubiquitin protein ligase |
| Alias Symbols |
PDJ, AR-JP, LPRS2, PARK2 |
| Product Format |
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Description of Target |
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. |
| Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PARK2 (OASG05678) antibody |
| Specificity |
Phospho-Parkin (S131) Polyclonal Antibody detects endogenous levels of Parkin protein only when phosphorylated at S131. |
| Application Info |
IHC 1:100-1:300; ELISA 1:20000; |
| Immunogen |
Synthesized peptide derived from human Parkin around the phosphorylation site of S131. Location: 70-150aa. |
| Uniprot ID |
O60260 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Target Post-Translational Modification |
Phospho-Ser131 |
| Gene Symbol |
PARK2 |
| Predicted Species Reactivity |
Human |
| Application |
IHC |
| Image 1 | 293T, AD293, HeLa,
 | Western Blot using 293T, AD293, HeLa, |
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