NFKB2 Antibody (OASG04980)

• Product Number: OASG04980
• Name: NFKB2 Antibody (OASG04980)
• Molecular Weight: 96 kDa
• Isotype: IgG
• NCBI Gene Id: 4791; 18034;
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Gene Full Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
• Alias Symbols: p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Description of Target: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Specificity: NFKappaB-p100 Polyclonal Antibody detects endogenous levels of NFKappaB-p100 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
• Immunogen: Synthesized peptide derived from human NFKappaB-p100 around the non-phosphorylation site of S869. Location: 810-890aa.
• Uniprot ID: Q00653, Q9WTK5
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Gene Symbol: NFKB2
• Predicted Species Reactivity: Human, Mouse, Rat
• Application: WB, IHC
• Image 1: Jurkat
  
  Western Blot using Jurkat
• Image 2: Jurkat
  
  Western Blot using Jurkat