| Product Number |
OASG02775 |
| Product Page |
www.avivasysbio.com/fosb-antibody-phospho-ser27-oasg02775.html |
| Name |
FOSB Antibody (Phospho-Ser27) (OASG02775) |
| Molecular Weight |
35 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
2354; 14282; |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
FBJ murine osteosarcoma viral oncogene homolog B |
| Alias Symbols |
AP-1, G0S3, GOS3, GOSB |
| Product Format |
Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Description of Target |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FOSB (OASG02775) antibody |
| Specificity |
Phospho-Fos B (S27) Polyclonal Antibody detects endogenous levels of Fos B protein only when phosphorylated at S27. |
| Additional Information |
Function: FosB interacts with Jun proteins enhancing their DNA binding activity.
Cellular Localization: Nucleus |
| Application Info |
WB: 1:500~2000
IHC: 1:100~300
IF: 1:200~1000
ELISA: 1:5000 |
| Immunogen |
Synthesized peptide derived from human Fos B around the phosphorylation site of S27. Location: 10-90aa. |
| Uniprot ID |
P53539, P13346 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Target Post-Translational Modification |
Phospho-Ser27 |
| Gene Symbol |
FOSB |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
WB, IHC, IF |
| Image 1 | |
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