MAPK6 Antibody (Phospho-Ser189) (OASG02581)

Data Sheet
 
Product Number OASG02581
Product Page www.avivasysbio.com/mapk6-antibody-phospho-ser189-oasg02581.html
Name MAPK6 Antibody (Phospho-Ser189) (OASG02581)
Molecular Weight 90 kDa
Isotype IgG
NCBI Gene Id 5597; 50772; 58840
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name mitogen-activated protein kinase 6
Alias Symbols ERK3, PRKM6, p97MAPK, HsT17250
Product Format Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Description of Target The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for anti-MAPK6 (OASG02581) antibody
Specificity Phospho-ERK 3 (S189) Polyclonal Antibody detects endogenous levels of ERK 3 protein only when phosphorylated at S189.
Application Info WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Immunogen Synthesized peptide derived from human ERK 3 around the phosphorylation site of S189. Location: 130-210aa.
Uniprot ID Q16659, Q61532, P27704
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Target Post-Translational Modification Phospho-Ser189
Gene Symbol MAPK6
Predicted Species Reactivity Human, Mouse, Rat
Application WB, IHC
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