ESR2 Antibody (Phospho-Ser105) (OASG02542)

• Product Number: OASG02542
• Name: ESR2 Antibody (Phospho-Ser105) (OASG02542)
• Molecular Weight: 59 kDa
• Isotype: IgG
• NCBI Gene Id: 2100; 13983; 25149
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Gene Full Name: estrogen receptor 2 (ER beta)
• Alias Symbols: Erb, ESRB, ODG8, ESTRB, NR3A2, ER-BETA, ESR-BETA
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Description of Target: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Specificity: Phospho-ERBeta (S105) Polyclonal Antibody detects endogenous levels of ERBeta protein only when phosphorylated at S105.
• Application Info: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000;
• Immunogen: Synthesized peptide derived from human ERBeta around the phosphorylation site of S105. Location: 40-120aa.
• Uniprot ID: Q92731, O08537, Q62986
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Target Post-Translational Modification: Phospho-Ser105
• Gene Symbol: ESR2
• Predicted Species Reactivity: Human, Mouse, Rat
• Application: WB, IF
• Image 1: HepG2
  
  Western Blot using HepG2