ACTN2 Antibody - N-terminal region (OASG00186)

Data Sheet
Product Number OASG00186
Product Page
Name ACTN2 Antibody - N-terminal region (OASG00186)
Molecular Weight 103 kDa
Isotype IgG
NCBI Gene Id 88; 89; 11472; 11472;
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name actinin, alpha 2
Alias Symbols MPD6, CMH23, CMD1AA, MYOCOZ
Product Format Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Description of Target Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ACTN2 (OASG00186) antibody
Specificity Actinin- Alpha2/3 Polyclonal Antibody detects endogenous levels of Actinin- Alpha2/3 protein.
Application Info WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
Immunogen Synthesized peptide derived from the N-terminal region of human Actinin- Alpha2/3. Location: 1-80aa.
Uniprot ID P35609, Q08043, Q9JI91, O88990
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Gene Symbol ACTN2, ACTN3
Predicted Species Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, WB
Image 1
Western Blot using HepG2
Image 2
HuvEc, MCF7, PC-12
Western Blot using HuvEc, MCF7, PC-12

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