Product Number |
OASG00186 |
Product Page |
www.avivasysbio.com/actn2-antibody-n-terminal-region-oasg00186.html |
Name |
ACTN2 Antibody - N-terminal region (OASG00186) |
Molecular Weight |
103 kDa |
Isotype |
IgG |
NCBI Gene Id |
88; 89; 11472; 11472; |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Gene Full Name |
actinin, alpha 2 |
Alias Symbols |
MPD6, CMH23, CMD1AA, MYOCOZ |
Product Format |
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Description of Target |
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. |
Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ACTN2 (OASG00186) antibody |
Specificity |
Actinin- Alpha2/3 Polyclonal Antibody detects endogenous levels of Actinin- Alpha2/3 protein. |
Application Info |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; |
Immunogen |
Synthesized peptide derived from the N-terminal region of human Actinin- Alpha2/3. Location: 1-80aa. |
Uniprot ID |
P35609, Q08043, Q9JI91, O88990 |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Gene Symbol |
ACTN2, ACTN3 |
Predicted Species Reactivity |
Human, Mouse, Rat |
Application |
WB, IHC, IF |
Image 1 | HepG2
| Western Blot using HepG2 |
| Image 2 | HuvEc, MCF7, PC-12
| Western Blot using HuvEc, MCF7, PC-12 |
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