MONOCYTES/MACROPHAGES Antibody (OASA11517)

Data Sheet
 
Product Number OASA11517
Product Page www.avivasysbio.com/monocytes-macrophages-antibody-oasa11517.html
Name MONOCYTES/MACROPHAGES Antibody (OASA11517)
Clone KUL01
Isotype IgG1
Host Mouse
Clonality Monoclonal
Concentration 0.5 mg/ml
Product Format Liquid. Borate buffered saline.
Description of Target MOUSE ANTI CHICKEN MONOCYTES/MACROPHAGES
Reconstitution and Storage -20°C
Datasheets/Manuals Printable datasheet for MONOCYTES/MACROPHAGES Antibody (OASA11517)
Specificity Mouse anti Chicken Monocytes/Macrophages, clone KUL01 recognises chicken monocytes and macrophages. Clone KUL01 will also detect interdigitating cells and activated microglia but does not recognise Bu1+ve B-cells or CD3 +ve T-lymphocytes.
Additional Information Buffer Solutions: Borate buffered saline.
Preservative Stabilisers: 0.09% Sodium azide
Application Info IHC-FFPE: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase
Purification Ion Exchange
Predicted Species Reactivity Chicken
Application FC, IHC-P, IP, MC, WB
Predicted Homology Based on Immunogen Sequence Chicken
Image 1

Immunohistochemical evidence of infiltration by T-cells (CD3+), B-cells (chB6+) and macrophages (Kul01+). Immunophenotyping identified the majority of infiltrating lymphocytes as being CD3-positive T-cells (A). They show a characteristic multifocal distribution pattern. With similar spatial characteristics, chB6-positive B-cells comprise the second largest fraction of infiltrating cells (B). Compared to the lymphocytes, the density of Kul01-positive macrophages appears much lower (C). The arrows point to immunopositive cells. All sections were prepared from the same region of the sciatic nerve. The orientation of the nerve fibres (NF) is indicated. Scale bar = 35 µm. From: Bader SR, Kothlow S, Trapp S, Schwarz SC, Philipp HC, Weigend S, Sharifi AR, Preisinger R, Schmahl W, Kaspers B, Matiasek K. Acute paretic syndrome in juvenile White Leghorn chickens
 

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