| Product Number |
OASA07470 |
| Product Page |
www.avivasysbio.com/bmp2-antibody-oasa07470.html |
| Name |
BMP2 Antibody (OASA07470) |
| Protein Size (# AA) |
396 amino acids |
| Isotype |
Polyclonal IgG |
| NCBI Gene Id |
650 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Alias Symbols |
BDA2, BMP2A, SSFSC, SSFSC1 |
| Product Format |
Purified IgG - liquid |
| Reference |
1. Balemans, W. and Van Hul, W. (2002) Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev. Biol. 250: 231-250.
2. Sebald, W. et al. (2004) Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction. Biol. Chem. 385: 697-710.
3. Keller, S. et al. (2004) Molecular recognition of BMP-2 and BMP receptor IA. Nature Structural and Molecular Biology. 11: 481-488.
4. Kirsch, T. et al. (2000) BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II. EMBO J. 19: 3314-3324.
5. Kimura, N. et al. (2000) BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6. J. Biol. Chem. 275: 17647-17652.
|
| Description of Target |
RABBIT ANTI HUMAN BMP-2
|
| Reconstitution and Storage |
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
|
| Datasheets/Manuals |
Printable datasheet for anti-BMP2 antibody - OASA07470 |
| Specificity |
BMP-2 |
| Additional Information |
Preservative Stabilisers: 0.09% - Sodium Azide (NaN3)
Antiserum Preparation: Antisera to human BMP-2 were raised by repeated immunisations of rabbits with highly purified antigen. |
| Application Info |
Dilution: 0.25 ug/ml. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. |
| Immunogen |
The immunogen for anti-BMP2 antibody: recombinant human BMP-2. |
| Additional Information |
Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4. |
| Uniprot ID |
P12643 |
| Protein Name |
Bone morphogenetic protein 2 |
| Protein Accession # |
NP_001191.1 |
| Gene Symbol |
BMP2 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | |
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