| Product Number |
OASA03361 |
| Product Page |
www.avivasysbio.com/tshr-antibody-oasa03361.html |
| Name |
TSHR Antibody (OASA03361) |
| Protein Size (# AA) |
764 amino acids |
| Clone |
4C1 |
| Isotype |
IgG2a |
| NCBI Gene Id |
7253 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Concentration |
1 mg/ml |
| Alias Symbols |
LGR3, CHNG1, hTSHR-I |
| Product Format |
Liquid. Phosphate buffered saline |
| Reference |
1. Suh, J. et al. (2003) Regulation of the phosphatidylinositol 3-Kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland. J. Biol. Chem. 278:21960-21971.
|
| Description of Target |
MOUSE ANTI HUMAN TSH RECEPTOR
|
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for TSHR Antibody (OASA03361) |
| Specificity |
Mouse anti Human thyroid stimulating hormone receptor, clone 4C1 recognises the human thyroid stimulating hormone receptor (hTSHR), otherwise known as the thyrotropin receptor. Mouse anti Human thyroid stimulating hormone binds to an extracellular domain of hTSHR. |
| Additional Information |
Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the NS1/Ag4.1 myeloma cell line.
Histology Positive Control Tissue: Thyroid gland |
| Additional Information |
Preservative Stabilisers: 0.09% - Sodium Azide |
| Application Info |
Flow Cytometry: 1/100 - 1/1000
Immunohistology - Paraffin: 1/1000 - 1/2000
Western Blotting: 1/1000
Flow Cytometry:Use 10ul of the suggested working dilution to label 106cells in 100ul. |
| Immunogen |
External domain of human TSH receptor. |
| Additional Information |
Approx Protein Conc: IgG concentration 1.0 mg/ml
Buffer Solutions: Phosphate buffered saline |
| Uniprot ID |
P16473 |
| Protein Name |
Thyrotropin receptor |
| Protein Accession # |
NP_000360.2 |
| Purification |
Protein A Purified |
| Gene Symbol |
TSHR |
| Predicted Species Reactivity |
Human |
| Application |
Flow cytometry|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Human thyroid
 | Staining of paraffin embedded human thyroid with Mouse anti Human TSH receptor |
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