| Product Number |
OAPB01594 |
| Product Page |
www.avivasysbio.com/abca7-antibody-n-terminal-oapb01594.html |
| Name |
ABCA7 Antibody - N-terminal (OAPB01594) |
| Molecular Weight |
Predicted: 236 kDa Observed: 240 kDa |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
10347 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
ATP binding cassette subfamily A member 7 |
| Alias Symbols |
ABCA-SSN;ABCX;AD9;ATP-binding cassette sub-family A member 7;ATP-binding cassette, sub-family A (ABC1), member 7;autoantigen SS-N;macrophage ABC transporter;phospholipid-transporting ATPase ABCA7. |
| Product Format |
Liquid. ABCA7 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Description of Target |
Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation. |
| Reconstitution and Storage |
ABCA7 antibody can be stored at 4C for three months and -20C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Datasheets/Manuals |
Printable datasheet for ABCA7 Antibody - N-terminal (OAPB01594) (OAPB01594) |
| Specificity |
ABCA7 antibody is predicted to not cross-react with other ABC1 subfamily proteins. |
| Additional Information |
Positive Control: 1) HEK293 Cell Lysate 2) Human Spleen Tissue |
| Application Info |
WB: 1-2 ug/mL
ICC: 5 ug/mL
IHC: 5 ug/mL
IF: 5 ug/mL
Optimal dilutions for each application to be determined by the researcher. |
| Immunogen |
ABCA7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ABCA7. The immunogen is located within amino acids 130 - 180 of ABCA7. |
| Intended Use |
For research use only. |
| Uniprot ID |
Q8IZY2 |
| Protein Name |
ATP-binding cassette sub-family A member 7|ATP-binding cassette sub-family A member 7 [Homo sapiens] |
| Protein Accession # |
https://www.ncbi.nlm.nih.gov/protein/NP_061985 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_019112.3 |
| Gene Symbol |
ABCA7 |
| Predicted Species Reactivity |
Human |
| Application |
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | 293 cell lysate
 | Western blot analysis of ABCA7 in 293 cell lysate with ABCA7 antibody at (A) 1 and (B) 2 ug/mL. |
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