AGTR1 Antibody (OAPB00959)

• Product Number: OAPB00959
• Name: AGTR1 Antibody (OAPB00959)
• Conjugation: Unconjugated
• NCBI Gene Id: 185
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Gene Full Name: angiotensin II receptor type 1
• Alias Symbols: AG2S;AGTR1B;Angiotensin II type-1 receptor;AT1;AT1AR;AT1B;AT1BR;AT1R;AT2R1;HAT1R;type-1 angiotensin II receptor;type-1B angiotensin II receptor.
• Product Format: Liquid. AGTR1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Reference: Mottl AK, Shoham DA, and North KE. Angiotensin II type 1 receptor polymorphisms and susceptibility to hypertension: A HuGE review. Gen. in Med.2008; 10:560-574.;Miyazaki Y and Ichikawa I. Role of the angiotensin receptor in the development of the mammalian kidney and urinary tract. Comp. Biochem. Physiol. A Mol. Integr. Physiol.2001; 128:89-97. ;Tsubakimoto Y, Yamada H, Yokoi H, et al. Bone marrow angiotensin AT1 receptor regulates differentiation of monocyte lineage progenitors from hematopoietic stem cells. Arterioscler. Thromb. Vasc. Biol.2009; 29:1529-36.;
• Description of Target: Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
• Reconstitution and Storage: AGTR1 antibody can be stored at 4C stable for three months. Stable for one year at -20C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Additional Information: Mouse Kidney Tissue Lysate (OCPB00082)
• Additional Information: Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Application Info: AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 ug/ml (Optimal dilution should be determined by user). For immunohistochemistry, start at 2.5ug/mL. For immunofluorescence, start at 20ug/mL.
• Blocking Peptide: For anti-AGTR1 antibody is Catalog # OEPB03075
• Immunogen: AGTR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1. The immunogen is located within amino acids 210 - 260 of AGTR1.
• Uniprot ID: P30556
• Protein Name: angiotensin II receptor, type 1, isoform CRA_a [Homo sapiens]|Type-1 angiotensin II receptor
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/EAW78909
• Purification: Affinity Purified
• Gene Symbol: AGTR1
• Predicted Species Reactivity: Bovine|Chicken|Guinea Pig|Human|Mouse|Porcine|Rabbit|Rat|Sheep
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Image 1: Mouse Kidney
  
  Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 ug/ml.
• Image 2: mouse kidney
  
  Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 ug/mL.
• Image 3: mouse kidney
  
  Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 ug/mL.