BAP3 Antibody (OAPB00643)

Data Sheet
 
Product Number OAPB00643
Product Page www.avivasysbio.com/bap3-antibody-oapb00643.html
Name BAP3 Antibody (OAPB00643)
Conjugation Unconjugated
NCBI Gene Id 8938
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name BAI1 associated protein 3
Alias Symbols BAI1-associated protein 3;BAI-associated protein 3;BAP3;brain-specific angiogenesis inhibitor I-associated protein 3.
Product Format Liquid. BAP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Reference Shiratsuchi T, Oda K, Nishimori H, et al. Cloning and characterization of BAP (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. Biochem. Biophys. Res. Comm.1998; 251:158-65. ;Palmer RE, Lee SB, Wong JC, et al. Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis. Cancer Cell2002; 2:497-505.;
Description of Target Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin (PubMed:28626000). Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission (By similarity).
Reconstitution and Storage BAP3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Datasheets/Manuals Printable datasheet for BAP3 Antibody (OAPB00643) (OAPB00643)
Additional Information Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Application Info BAP3 antibody can be used for the detection of BAP3 by Western blot at 2 ug/ml. (Optimal dilution should be determined by user)
Blocking Peptide For anti-BAP3 antibody is Catalog # OEPB02767
Immunogen BAP3 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human BAP3. The immunogen is located within the first 50 amino acids of BAP3.
Uniprot ID O94812
Protein Name BAI1-associated protein 3|BAI-associated protein 3 [Homo sapiens]
Protein Accession # https://www.ncbi.nlm.nih.gov/protein/BAA34710
Purification Affinity Purified
Gene Symbol BAIAP3
Predicted Species Reactivity Human
Application Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Predicted Homology Based on Immunogen Sequence Human
Image 1
SK-N-SH
Western blot analysis of BAP3 in SK-N-SH cell lysate with BAP3 antibody at 2 ug/mL.
Image 2
Human brain
Immunohistochemical staining of human brain tissue using BAP3 antibody at 2.5 ug/mL.
 

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