ACE2 Antibody : Biotin (OAPB00220-Biotin)

Data Sheet
 
Product Number OAPB00220-Biotin
Product Page www.avivasysbio.com/ace2-antibody-biotin-oapb00220-biotin.html
Name ACE2 Antibody : Biotin (OAPB00220-Biotin)
Conjugation Biotin
NCBI Gene Id 59272
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Alias Symbols ACEH
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Reference Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotension I to angiotension 1-9. Circ. Res. 2000;87:1-9.;Tipnis SR, Hooper NM, Hyde R, et al. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol. Chem. 2000;275:33238-43.;Li W, Moore MJ, Vasileva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003;426:450-4.
;Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002;417:822-8.
Description of Target (IN2) Angiotensin-converting enzyme 2, SARS receptor
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-ACE2 antibody - OAPB00220-Biotin
Specificity Anti-ACE2 has no cross response to ACE1.
Additional Information Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Application Info ACE2 antibody can be used for the detection of ACE2 by Western blot at 0.5 to 2 ug/ml. A 90 kDa band can be detected. Anti-ACE2 has no cross response to ACE1. (Optimal dilution should be determined by user)
Blocking Peptide For anti-ACE2 antibody is Catalog # OEPB02314
Immunogen The immunogen for anti-ACE2 antibody: antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ACE2.
Uniprot ID Q9BYF1
Protein Name Angiotensin-converting enzyme 2
Protein Accession # NP_068576
Purification Affinity chromatography purified via peptide column
Gene Symbol ACE2
Predicted Species Reactivity Human
Application ELISA, WB, IHC
Predicted Homology Based on Immunogen Sequence Human
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