Muc1 Antibody (OAMA02431)

Data Sheet
 
Product Number OAMA02431
Product Page www.avivasysbio.com/muc1-antibody-oama02431.html
Name Muc1 Antibody (OAMA02431)
Clone M9E7
Isotype IgG
NCBI Gene Id 4582
Host Mouse. Source: Ascites
Clonality Monoclonal
Purity >90% pure (SDS-PAGE). Protein A chromatography
Alias Symbols EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADTKD2, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
Product Format Purified, Liquid. Supplied in Phosphate Buffered Saline, pH 7.4, 0.09% Sodium Azide
Reconstitution and Storage Store at 2-8C.
Datasheets/Manuals Printable datasheet for anti-Muc1 antibody - OAMA02431
Specificity Reacts with high efficiency with different regions of GVTSAPDTRPAPGSTAPPAHGVTSA synthetic peptide spanning the repeat of VNTR extracellular portion of MUC1 molecule. Reacts with VNTR5 and VNTR20 recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1 prepared from tumor fluids (T47D cell) or as a result of chemical treatment (NaJO4) of human milk MUC1. It does not react with natural MUC1 protein isolated from human milk by affinity purification on carbohydrate epitope specific MAbs and belong to MAb cluster 1-4 according to ISOMB TD-4 classification. No crossreactivity with egg white avidin.
Application Info Suitable for use in Immunohistochemical and Immunofluorescent detection of neoplastic breast epithelium (frozen sections). May be used development of highly effective ELISA tests for unglycosylated and underglycosylated tumorassociated MUC1 mucins in human serum. May also be used for the solid-phase capture of MUC1 isoforms. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Immunogen Recombinant (E.coli) VENTR20 (tandem repeat in MUC1 core) polypeptide
Uniprot ID P15941
Protein Name Mucin-1
Protein Accession # NP_001018016.1
Gene Symbol Muc1
Predicted Species Reactivity Human
Application IHC-F, EIA, Pr
Predicted Homology Based on Immunogen Sequence Human
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