| Product Number |
OAMA02375 |
| Product Page |
www.avivasysbio.com/muc1-antibody-oama02375.html |
| Name |
Muc1 Antibody (OAMA02375) |
| Clone |
M2F1 |
| Isotype |
IgG |
| NCBI Gene Id |
4582 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Purity |
>90% pure (SDS-PAGE) |
| Concentration |
7.4 mg/ml (OD280nm, E0.1%=1.4) |
| Source |
Ascites |
| Alias Symbols |
EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADTKD2, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC |
| Product Format |
Liquid PBS (pH 7.4) with 0.09% sodium azide |
| Reconstitution and Storage |
Store at 2-8°C. |
| Datasheets/Manuals |
Printable datasheet for anti-Muc1 antibody - OAMA02375 |
| Specificity |
Binds with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule. Efficiently recognizes underglycosylated and natural MUC1 protein isolated from human milk by affinity chromatography. Belongs to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Does not cross-react with normal serum proteins and human tissues of nonepithelial origin. |
| Application Info |
Suitable for use in Immunohistochemical and Immunofluorescent detection of neoplastic breast epithelium, and breast, lung and ovarian tumor tissues (frozen and paraffin) MUC1 are abundantly present on the surface of growing tumor cell lines and on the surface and cytoplasm of malignant cells of epithelial origin. May be used development of highly effective ELISA tests for unglycosylated and underglycosylated tumorassociated MUC1 mucins in human serum. May also be used for the solid-phase capture of MUC1 isoforms. Each laboratory should determine an optimum working titer for use in its particular application.
|
| Immunogen |
High molecular weight (> 300 kDa) glycoprotein from human milk-fat globule molecule. |
| Uniprot ID |
P15941 |
| Protein Name |
Mucin-1 |
| Protein Accession # |
NP_001018016.1 |
| Purification |
Protein A Chromatography |
| Gene Symbol |
Muc1 |
| Predicted Species Reactivity |
Human |
| Application |
IHC-F, IHC-P, EIA, Pr |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | |
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