Muc1 Antibody (OAMA01337)

Data Sheet
 
Product Number OAMA01337
Product Page www.avivasysbio.com/muc1-antibody-oama01337.html
Name Muc1 Antibody (OAMA01337)
Clone M4H2
Isotype IgG
NCBI Gene Id 4582
Host Mouse
Clonality Monoclonal
Purity >90% pure (SDS-PAGE)
Concentration 7.1 mg/ml (OD280nm, E0.1%=1.4)
Source Ascites
Alias Symbols EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADTKD2, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
Product Format Liquid PBS (pH 7.4) with 0.09% sodium azide
Reconstitution and Storage Store at 2 to 8°C.
Datasheets/Manuals Printable datasheet for OAMA01337
Specificity Binds with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule. Reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein, with monomeric VNTR MUC1 peptide, with deglycosylated and underglycosylated natural MUC1. Belongs to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross reactive with normal serum proteins and human tissues of nonepithelial origin.
Application Info Suitable for use in Immunohistochemical and Immunofluorescent detection of neoplastic breast epithelium, and breast, lung and ovarian tumor tissues (frozen and paraffin) MUC1 are abundantly present on the surface of growing tumor cell lines and on the surface and cytoplasm of malignant cells of epithelial origin. May be used development of highly effective ELISA tests for unglycosylated and underglycosylated tumor associated MUC1 mucins in human serum. May also be used for the solid-phase capture of MUC1 isoforms.
Immunogen Recombinant (E.coli) VNTR20 (tandem repeat in MUC1 core) polypeptide
Uniprot ID P15941
Protein Name Mucin-1
Protein Accession # NP_001018016.1
Purification Protein A Chromatography
Application IHC-F, IHC-P, EIA, Pr
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