ARID1A Antibody (OAGA07498)

Data Sheet
 
Product Number OAGA07498
Product Page www.avivasysbio.com/arid1a-antibody-oaga07498.html
Name ARID1A Antibody (OAGA07498)
Isotype IgG
NCBI Gene Id 8289
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name AT-rich interaction domain 1A
Alias Symbols ELD, B120, CSS2, OSA1, P270, hELD, BM029, MRD14, hOSA1, BAF250, C1orf4, BAF250a, SMARCF1
Product Format Liquid
Description of Target This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
Reconstitution and Storage Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAGA07498
Application Info Suggested starting dilutions are as follows: WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A. The exact sequence is proprietary.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Uniprot ID O14497
Protein Name AT-rich interactive domain-containing protein 1A
Protein Accession # NP_006006.3
Purification Purified by antigen-affinity chromatography.
Nucleotide Accession # NM_006015.4
Preservative 0.025% ProClin 300
Gene Symbol ARID1A
Predicted Species Reactivity Human
Application WB
Image 1
293T whole cell
ARID1A antibody detects ARID1A protein by western blot analysis.
A. 30 ug 293T whole cell lysate/extract
B. 30 ug whole cell lysate/extract of human ARID1A-transfected 293T cells
5 % SDS-PAGE
ARID1A antibody dilution: 1:5000
 

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