ADAM10 Antibody - middle region (OAGA02442)

Data Sheet
 
Product Number OAGA02442
Product Page www.avivasysbio.com/adam10-antibody-middle-region-oaga02442.html
Name ADAM10 Antibody - middle region (OAGA02442)
Molecular Weight 84 kDa
Isotype IgG
NCBI Gene Id 102
Host Rabbit
Clonality Polyclonal
Concentration Varies by lot. See vial for concentration.
Gene Full Name ADAM metallopeptidase domain 10
Description
Alias Symbols RAK, kuz, AD10, AD18, MADM, CD156c, CDw156, HsT18717
Product Format Liquid.0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Description of Target Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.
Reconstitution and Storage Store as a concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ADAM10 (OAGA02442) antibody
Application Info WB 1:500~3000
IHC-P 1:100~1000
Immunogen Recombinant protein encompassing a sequence within the center region of human ADAM10. The exact sequence is proprietary.
Uniprot ID O14672
Publications

Sogorb-Esteve, A., García-Ayllón, M., Gobom, J., Alom, J., Zetterberg, H., Blennow, K. and Sáez-Valero, J. Levels of ADAM10 are reduced in Alzheimer’s disease CSF. J Neuroinflammation. 15, 213 (2018). 30045733

α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer's disease. Alzheimers Res Ther. 12, 139 (2020). 33129344

Purification Purified by antigen-affinity chromatography.
Gene Symbol ADAM10
Predicted Species Reactivity Human
Application IHC-P, WB
Image 1
Paraffin-embedded Lung Papillary Adenocarcinoma
Immunohistochemical analysis of paraffin-embedded Lung Papillary Adenocarcinoma, using ADAM10 (OAGA02442) antibody at 1:250 dilution.
Image 2
THP-1
Sample (30 ug of whole cell lysate)
A: THP-1
7.5% SDS PAGE
OAGA02442 diluted at 1:1000
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com