Product Number |
OAGA02442 |
Product Page |
www.avivasysbio.com/adam10-antibody-middle-region-oaga02442.html |
Name |
ADAM10 Antibody - middle region (OAGA02442) |
Molecular Weight |
84 kDa |
Isotype |
IgG |
NCBI Gene Id |
102 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Varies by lot. See vial for concentration. |
Gene Full Name |
ADAM metallopeptidase domain 10 |
Description |
|
Alias Symbols |
RAK, kuz, AD10, AD18, MADM, CD156c, CDw156, HsT18717 |
Product Format |
Liquid.0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Description of Target |
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. |
Reconstitution and Storage |
Store as a concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ADAM10 (OAGA02442) antibody |
Application Info |
WB 1:500~3000 IHC-P 1:100~1000 |
Immunogen |
Recombinant protein encompassing a sequence within the center region of human ADAM10. The exact sequence is proprietary. |
Uniprot ID |
O14672 |
Publications |
Sogorb-Esteve, A., GarcÃa-Ayllón, M., Gobom, J., Alom, J., Zetterberg, H., Blennow, K. and Sáez-Valero, J. Levels of ADAM10 are reduced in Alzheimerâs disease CSF. J Neuroinflammation. 15, 213 (2018). 30045733
α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer's disease. Alzheimers Res Ther. 12, 139 (2020). 33129344 |
Purification |
Purified by antigen-affinity chromatography. |
Gene Symbol |
ADAM10 |
Predicted Species Reactivity |
Human |
Application |
IHC-P, WB |
Image 1 | Paraffin-embedded Lung Papillary Adenocarcinoma
| Immunohistochemical analysis of paraffin-embedded Lung Papillary Adenocarcinoma, using ADAM10 (OAGA02442) antibody at 1:250 dilution. |
| Image 2 | THP-1
| Sample (30 ug of whole cell lysate) A: THP-1 7.5% SDS PAGE OAGA02442 diluted at 1:1000
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