| Product Number |
OAGA00741 |
| Product Page |
www.avivasysbio.com/mtap-antibody-oaga00741.html |
| Name |
MTAP Antibody (OAGA00741) |
| Molecular Weight |
31 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
4507 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
S-methyl-5'-thioadenosine phosphorylase |
| Alias Symbols |
BDMF, MSAP, DMSFH, LGMBF, DMSMFH, c86fus, HEL-249 |
| Product Format |
Liquid |
| Reconstitution and Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MTAP antibody - OAGA00741 |
| Additional Information |
Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq] |
| Additional Information |
Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver |
| Application Info |
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Immunogen |
Recombinant fragment corresponding to a region within amino acids 1 and 283 of MTAP (Uniprot ID#Q13126) |
| Additional Information |
Cellular Localization: Cytoplasm |
| Storage Buffer |
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Uniprot ID |
Q13126 |
| Protein Name |
S-methyl-5'-thioadenosine phosphorylase |
| Protein Accession # |
NP_002442.2 |
| Purification |
Purified by antigen-affinity chromatography. |
| Gene Symbol |
MTAP |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
IHC-FFPE, WB |
| Image 1 | A431
 | Sample (30 ug of whole cell lysate)
A: A431
12% SDS PAGE
OAGA00741 diluted at 1:1000 |
| | Image 2 | mouse liver
 | Sample (50 ug of whole cell lysate)
A: mouse liver
12% SDS PAGE
OAGA00741 diluted at 1:1000
|
| | Image 3 | SAS Xenograft
 | Immunohistochemical analysis of paraffin-embedded SAS xenograft, using MTAP(OAGA00741) antibody at 1:500 dilution. |
|
|
