| Product Number |
OAGA00507 |
| Product Page |
www.avivasysbio.com/rgs17-antibody-oaga00507.html |
| Name |
RGS17 Antibody (OAGA00507) |
| Molecular Weight |
24 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
26575 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
Regulator of G-protein signaling 17 |
| Alias Symbols |
RGSZ2, RGS-17, hRGS17 |
| Product Format |
Liquid |
| Reconstitution and Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RGS17 antibody - OAGA00507 |
| Additional Information |
Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq] |
| Additional Information |
Positive Controls: 293T transfected recombinant RGS17 |
| Application Info |
Suggested starting dilutions are as follows: WB: 1:1000-1:10000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Immunogen |
Synthetic peptide corresponding to a region within amino acids 148 and 210 of RGS17 (Uniprot ID#Q9UGC6) |
| Additional Information |
Cellular Localization: Membrane; Lipid-anchor, Nucleus, Cytoplasm |
| Storage Buffer |
1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Uniprot ID |
Q9UGC6 |
| Protein Name |
Regulator of G-protein signaling 17 |
| Protein Accession # |
NP_036551.3 |
| Purification |
Purified by antigen-affinity chromatography. |
| Gene Symbol |
RGS17 |
| Predicted Species Reactivity |
Human |
| Application |
ICC, IF, WB |
| Image 1 | Non-transfected 293T lysates , RGS17 transfected 293T lysates
 | Sample (30 ug of whole cell lysate)
A: Non-transfected 293T lysates
B: RGS17 transfected 293T lysates
12% SDS PAGE
OAGA00507 diluted at 1:5000
|
| | Image 2 | A431
 | Immunofluorescence analysis of paraformaldehyde-fixed A431, using RGS17(OAGA00507) antibody at 1:200 dilution. |
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