| Product Number |
OAGA00341 |
| Product Page |
www.avivasysbio.com/socs5-antibody-oaga00341.html |
| Name |
SOCS5 Antibody (OAGA00341) |
| Molecular Weight |
61 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
9655 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
Suppressor of cytokine signaling 5 |
| Alias Symbols |
CIS6, CISH6, Cish5, SOCS-5 |
| Product Format |
Liquid |
| Reconstitution and Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SOCS5 antibody - OAGA00341 |
| Additional Information |
Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq] |
| Additional Information |
Positive Controls: Molt-4, NT2D1, PC-3, mouse testis |
| Application Info |
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Immunogen |
Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 42 of SOCS5 |
| Storage Buffer |
1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Uniprot ID |
O75159 |
| Protein Name |
Suppressor of cytokine signaling 5 |
| Protein Accession # |
NP_054730.1 |
| Purification |
Purified by antigen-affinity chromatography. |
| Gene Symbol |
SOCS5 |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
IHC-FFPE, WB |
| Image 1 | Molt-4
 | Sample (30 ug of whole cell lysate)
A: Molt-4
7.5% SDS PAGE
SOCS5 antibody
OAGA00341 diluted at 1:1000
|
| | Image 2 | mouse testis
 | SOCS5 antibody detects SOCS5 protein by Western blot analysis.
A. 50 ug mouse testis lysate/extract
7.5 % SDS-PAGE
SOCS5 antibody (OAGA00341) dilution: 1:500 |
| | Image 3 | NT2D1
 | SOCS5 antibody detects SOCS5 protein by Western blot analysis.
A. 30 ug NT2D1 whole cell lysate/extract
B. 30 ug PC-3 whole cell lysate/extract
7.5 % SDS-PAGE
SOCS5 antibody (OAGA00341) dilution: 1:500 |
| | Image 4 | Ca922 Xenograft
 | Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using SOCS5(OAGA00341) antibody at 1:100 dilution. |
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