| Product Number |
OAED00073 |
| Product Page |
www.avivasysbio.com/prkca-antibody-oaed00073.html |
| Name |
PRKCA Antibody (OAED00073) |
| Molecular Weight |
8 |
| Clone |
MC5 |
| Isotype |
IgG2a |
| NCBI Gene Id |
5578 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Gene Full Name |
Protein kinase C alpha type |
| Alias Symbols |
AAG6, PKCA, PRKACA, PKCI+/-, PKCalpha, PKC-alpha |
| Product Format |
Liquid. PBS, pH 7.2 containing 50% glycerol and 0.09% sodium azide. |
| Description of Target |
Protein Kinase C (PKC) is a large superfamily of serine/threonine kinases that mediate essential cellular signals required for activation, proliferation, differentiation and survival. There are at least ten PKC isotypes that are closely related in structure but that have distinct patterns of tissue distribution and function. The PKC isotypes can be subdivided into three classes based on primary structure and biochemical properties. These are: classical or conventional PKC isotypes (cPKC), novel PKC isotypes (nPKC) and atypical PKC isotypes (aPKC). |
| Reconstitution and Storage |
Store at -20C. |
| Datasheets/Manuals |
Printable datasheet for anti-PRKCA (OAED00073) antibody |
| Specificity |
Detects a band of ~80kDa by Western blot. |
| Application Info |
FC 10 ug/ml
IHC 1:50 (tested in human lung, carcinoma tissue)
IP 12.5 ug/ml
WB 1:1000 |
| Immunogen |
Bovine brain PKCalpha. |
| Uniprot ID |
P17252 |
| Protein Name |
Protein kinase C alpha type |
| Protein Accession # |
NP_002728.1 |
| Purification |
Protein G affinity purified.< |
| Nucleotide Accession # |
NM_002737.2 |
| Gene Symbol |
PRKCA |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
FC, IF, IHC, IP, WB |
| Predicted Homology Based on Immunogen Sequence |
Bovine, Dog, Fish, Gerbil, Monkey, Pig, Rabbit, Sheep Chicken, Horse, Pig, Sheep |
| Image 1 | HeLa cell lysate, mouse brain tissue extract, rat brain tissue extract, 3T3 cell lysate
 | Western blot analysis: Lane 1: MW marker; Lane 2: HeLa cell lysate; Lane 3: mouse brain tissue extract; Lane 4: rat brain tissue extract; Lane 5: 3T3 cell lysate, probed with PKCalpha, mAb (MC5). |
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