| Product Number |
OAEC04713 |
| Product Page |
www.avivasysbio.com/stk11-antibody-oaec04713.html |
| Name |
STK11 Antibody (OAEC04713) |
| Molecular Weight |
54 kDa |
| Clone |
4H12 |
| Isotype |
IgG1 |
| NCBI Gene Id |
6794 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
serine/threonine kinase 11 |
| Alias Symbols |
PJS, LKB1, hLKB1 |
| Product Format |
Ascitic fluid containing 0.03% sodium azide |
| Description of Target |
Es sential role in G1 cell cycle arrest. Phosphorylates and activates members of theAMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase11, with two alternatively spliced isoforms, expres sed in all tissues, s trongly homolog of Xenopus early embryonic kinase 1 (XEEK1), tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis, mutated in sporadic testicular cancer, malignant melanomas and laryngeal tumors, playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity Ubiquitously expressed. Strongest expres sion in tes tis and fetal liver. |
| Reconstitution and Storage |
Store at 4C, for long term storage, store at -20C. |
| Datasheets/Manuals |
Printable datasheet for anti-STK11 (OAEC04713) antibody |
| Immunogen |
Purified recombinant fragment of human STK11 expressed in E. Coli. |
| Uniprot ID |
Q15831 |
| Gene Symbol |
STK11 |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
WB, FC |
| Image 1 | K562 cells
 | Flow cytometric analysis of K562 cells using STK11 mouse mAb (green) and negative control (purple). |
| | Image 2 | NIH/3T3 (1), Raw246.7 (2), COS7 (3), Jurkat (4), HEK293 (5) and A431 (6) cell lysate
 | Western blot analysis using STK11 mouse mAb against NIH/3T3 (1), Raw246.7 (2), COS7 (3), Jurkat (4), HEK293 (5) and A431 (6) cell lysate. |
|
|
