| Product Number |
OAEC04270 |
| Product Page |
www.avivasysbio.com/orf8-antibody-oaec04270.html |
| Name |
ORF8 Antibody (OAEC04270) |
| Isotype |
IgG1 |
| NCBI Gene Id |
4961501 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
envelope glycoprotein gB |
| Product Format |
Rabbit anti-serum |
| Description of Target |
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lym phoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-As p (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells. |
| Reconstitution and Storage |
Store at 4C, for long term storage, store at -20C. |
| Datasheets/Manuals |
Printable datasheet for anti-ORF8 (OAEC04270) antibody |
| Application Info |
WB: 1/500 - 1/2000
ELISA: 1/10000
|
| Immunogen |
Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. |
| Uniprot ID |
F5HB81 |
| Gene Symbol |
ORF8 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | Uninduced BCBL1 cell lysate (1), TPA induced BCBL1 cell lysate (2) and purified virion (3)
 | Western blot analysis using anti-KSHV ORF8 polyclonal antiobdy against uninduced BCBL1 cell lysate (1), TPA induced BCBL1 cell lysate (2) and purified virion (3). |
|
|
