| Product Number |
OAEB02180 |
| Product Page |
www.avivasysbio.com/goat-anti-sur1-abcc8-antibody-oaeb02180.html |
| Name |
Goat Anti-SUR1 / ABCC8 Antibody (OAEB02180) |
| Molecular Weight |
177 |
| NCBI Gene Id |
20927|25559|6833 |
| Host |
Goat |
| Clonality |
Polyclonal |
| Purity |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
ATP binding cassette subfamily C member 8|ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| Alias Symbols |
ABC36;ATP-binding cassette sub-family C member 8;ATP-binding cassette transporter sub-family C member 8;ATP-binding cassette, subfamily C (CFTR/MRP), member 8;ATP-binding cassette, sub-family C (CFTR/MRP), member 8;D930031B21Rik;HHF1;HI;HRINS;MRP8;PHHI;PNDM3;S;SU;sulfonylurea receptor;sulfonylurea receptor (hyperinsulinemia);sulfonylurea receptor 1;sulphonylurea receptor 1;Sur;Sur1;SUR1delta2;TNDM2. |
| Peptide Sequence |
C-EFDKPEKLLSRKD |
| Product Format |
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reference |
* de Wet H, Rees MG, Shimomura K, Aittoniemi J, Patch AM, Flanagan SE, Ellard S, Hattersley AT, Sansom MS, Ashcroft FM.; Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes.; Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18988-92.; Pubmed 18025464 |
| Reconstitution and Storage |
Aliquot and store at -20C. Minimize freezing and thawing. |
| Datasheets/Manuals |
Printable datasheet for Goat Anti-SUR1 / ABCC8 Antibody (OAEB02180) |
| Application Info |
Peptide ELISA: antibody detection limit dilution 1:8000.
Western Blot: Approx 170kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177kDa according to NP_000343.2). Recommended concentration: 0.5-1.5ug/ml.
An additional band of unknown identity was also consistently observed at 23kDa. This band was successfully blocked by incubation with the immunising peptide. |
| Immunogen |
ABCC8 |
| Uniprot ID |
Q09428 |
| Protein Name |
ATP-binding cassette sub-family C member 8 |
| Protein Accession # |
NP_000343.2 |
| Purification |
Ammonium Sulfate Precipitated; Affinity Purified |
| Gene Symbol |
Abcc8|ABCC8 |
| Predicted Species Reactivity |
Dog|Human|Mouse|Rat |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 92%; Rat: 92% |
| Image 1 | Human Cerebellum
 | OAEB02180 (0.5ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
|
|
