Goat Anti-ATP6IP2 / Renin receptor Antibody (OAEB01325)

Data Sheet
Product Number OAEB01325
Product Page www.avivasysbio.com/goat-anti-atp6ip2-renin-receptor-antibody-oaeb01325.html
Name Goat Anti-ATP6IP2 / Renin receptor Antibody (OAEB01325)
NCBI Gene Id 10159
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols PRR, M8-9, MRXE, RENR, XMRE, XPDS, CDG2R, HT028, MRXSH, ELDF10, ATP6IP2, MSTP009, APT6M8-9, ATP6M8-9
Product Format Liquid Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reference * Advani A, Kelly DJ, Cox AJ, White KE, Advani SL, Thai K, Connelly KA, Yuen D, Trogadis J, Herzenberg AM, Kuliszewski MA, Leong-Poi H, Gilbert RE.; The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney.; Hypertension. 2009 Aug;54(2):261-9.; Pubmed 19546380
* Schefe JH, Neumann C, Goebel M, Danser J, Kirsch S, Gust R, Kintscher U, Unger T, Funke-Kaiser H.; Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren.; J Hypertens. 2008 Sep;26(9):1787-94.; Pubmed 18698213
* Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AH, Uddin MN, Nakagawa T, Nishiyama A, Suzuki F, Inagami T, Itoh H.; Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats.; J Am Soc Nephrol. 2007 Jun;18(6):1789-95.; Pubmed 17494887
* Ludwig J, Kerscher S, Brandt U, Pfeiffer K, Getlawi F, Apps DK, Schagger H.; Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.; J Biol Chem. 1998 May 1;273(18):10939-47.; Pubmed 9556572
Reconstitution and Storage Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals Printable datasheet for anti-ATP6AP2 antibody - OAEB01325
Application Info P-ELISA: Antibody detection limit dilution 1:16000
WB: Approx 37 kDa band observed in Human Kidney lysates (calculated MW of 39.0kDa according to NP_005756.2). Recommended concentration: 0.25-1 ug/ml
IHC: This antibody has been successfully used on Human tissue in the following papers: Pringle et al, J Renin Angiotensin Aldosterone Syst. 2010 Aug 11, PMID: 20702505. Delforce et al, Endocr Connect. 2017 Jan;6(1):9-19, PMID: 27956412.
Immunogen Peptide with sequence C-SIIYRMTNQKIRMD, from the C Terminus of the protein sequence according to NP_005756.2.
Uniprot ID O75787
Protein Name Renin receptor
Protein Accession # NP_005756.2
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Gene Symbol ATP6AP2
Predicted Species Reactivity Human
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Human, Rat
Image 1
Human Kidney
OAEB01325 staining (0.5ug/ml) of Human Kidney lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

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