CACNA2D1 Antibody (OAEB01261)

Data Sheet
 
Product Number OAEB01261
Product Page www.avivasysbio.com/cacna2d1-antibody-oaeb01261.html
Name CACNA2D1 Antibody (OAEB01261)
Molecular Weight 123
NCBI Gene Id 12293|25399|781
Host Goat
Clonality Polyclonal
Purity Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration 0.5 mg/ml
Gene Full Name calcium channel, voltage-dependent, alpha2/delta subunit 1|calcium voltage-gated channel auxiliary subunit alpha2delta 1
Description
Alias Symbols Ca(v)alpha2delta1;Cac;Cacna2;CACNL2A;Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type);calcium channel, L type, alpha 2 polypeptide;calcium channel, voltage-dependent, alpha 2/delta subunit 1;calcium channel, voltage-dependent, alpha2/delta subunit 1;Cchl;Cchl2a;CCHLA2;DHSCCA;dihydropyridine-sensitive calcium channel alpha 2;dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit;LINC01112;lncRNA-N3;voltage-dependent calcium channel alpha2/delta-1;voltage-dependent calcium channel subunit alpha-2/delta-1;voltage-gated calcium channel subunit alpha-2/delta-1.
Peptide Sequence C-QEIFNKYNKDKKVR
Product Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Reference * Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D'Souza K, Friedrich Khan I, Rottlander D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bunemann M, Hein L, Schwartz A, Herzig S.; Increased Expression of the Auxiliary beta(2)-subunit of Ventricular L-type Ca Channels Leads to Single-Channel Activity Characteristic of Heart Failure.; PLoS ONE. 2007 Mar 14;2:e292.; Pubmed 17356701
Reconstitution and Storage Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals Printable datasheet for CACNA2D1 Antibody (OAEB01261)
Application Info Peptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: Approx 140kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123kDa according to NP_000713.2). Recommended concentration: 0.03-0.1ug/ml.
Immunogen CACNA2D1
Uniprot ID O95026
Protein Name Putative uncharacterized protein CACNA2D1 EMBL AAC78619.1
Publications

Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). 21357696

Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway. Cardiovasc Res. 101, 288-96 (2014) 24233972

Protein Accession # NP_000713.2
Purification Ammonium Sulfate Precipitated; Affinity Purified
Gene Symbol Cacna2d1|CACNA2D1
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%
Image 1
Human Brain (Cerebellum)
OAEB01261 (0.03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com