| Product Number |
OAEB00935 |
| Product Page |
www.avivasysbio.com/gabrb3-antibody-oaeb00935.html |
| Name |
GABRB3 Antibody (OAEB00935) |
| Molecular Weight |
54.1; 54.4 |
| NCBI Gene Id |
14402|24922|2562 |
| Host |
Goat |
| Clonality |
Polyclonal |
| Purity |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3|gamma-aminobutyric acid type A receptor subunit beta 3|gamma-aminobutyric acid type A receptor subunit beta3 |
| Alias Symbols |
A230092K12Rik;AW049585;beta3;cleft palate 1;Cp1;DEE43;ECA5;EIEE43;GABA(A) receptor subunit beta-3;GABAA receptor beta-3 subunit;GABA-alpha receptor beta-2 subunit;GABA-alpha receptor beta-3 subunit;Gabrb;Gabrb-3;gamma-aminobutyric acid (GABA) A receptor, beta 3;gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3;gamma-aminobutyric acid A receptor beta 3;Gamma-aminobutyric acid receptor beta 3;gamma-aminobutyric acid receptor subunit beta-3;gamma-aminobutyric acid type A receptor beta 3 subunit;gamma-aminobutyric acid type A receptor beta3 subunit;testis gamma-aminobutyric acid receptor subunit beta 3. |
| Peptide Sequence |
C-EKTAKAKNDRSK |
| Product Format |
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Reference |
* Tanaka M, Olsen RW, Medina MT, Schwartz E, Alonso ME, Duron RM, Castro-Ortega R, Martinez-Juarez IE, Pascual-Castroviejo I, Machado-Salas J, Silva R, Bailey JN, Bai D, Ochoa A, Jara-Prado A, Pineda G, Macdonald RL, Delgado-Escueta AV.; Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy.; Am. J. Hum. Genet. 2008 Jun 82 (6): 1249-61.; Pubmed 18514161 |
| Reconstitution and Storage |
Aliquot and store at -20C. Minimize freezing and thawing. |
| Datasheets/Manuals |
Printable datasheet for GABRB3 Antibody (OAEB00935) |
| Application Info |
Peptide ELISA: antibody detection limit dilution 1:8000.
Western Blot: Preliminary experiments in Human Brain (Cerebral Cortex, Frontal Cortex and Cerebellum) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). |
| Immunogen |
GABRB3 |
| Uniprot ID |
P28472 |
| Protein Name |
Gamma-aminobutyric acid receptor subunit beta-3 |
| Protein Accession # |
NP_000805.1 |
| Purification |
Ammonium Sulfate Precipitated; Affinity Purified |
| Gene Symbol |
Gabrb3|GABRB3 |
| Predicted Species Reactivity |
Bovine|Dog|Human|Mouse|Rat |
| Application |
IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 91%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 91%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Cortex
 | OAEB00935 (2.5ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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