POLR2A Antibody (OADC00205)

Data Sheet
 
Product Number OADC00205
Product Page www.avivasysbio.com/polr2a-antibody-oadc00205.html
Name POLR2A Antibody (OADC00205)
Isotype IgG1
Conjugation Unconjugated
NCBI Gene Id 5430;
Host Mouse
Clonality Monoclonal
Concentration 1 mg/mL
Gene Full Name polymerase (RNA) II subunit A
Alias Symbols RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, NEDHIB, RpIILS, hsRPB1, hRPB220
Product Format Liquid. Provided in PBS containing 0.05% azide.
Description of Target This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for anti-POLR2A (OADC00205) antibody
Specificity Mouse monoclonal antibody raised against SIRT1
Application Info CHIP: 1 ug/CHIP
ELISA: 1:3,000
Western Blotting: 1:1,000
Immunofluorescence: 1:500
Uniprot ID P24928
Protein Name DNA-directed RNA polymerase II subunit RPB1
Protein Accession # NP_000928.1
Purification Protein A purified
Nucleotide Accession # NM_000937.4
Preservative 0.05% Sodium Azide
Gene Symbol POLR2A
Predicted Species Reactivity Human
Application CHIP, WB, IF
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