CD13 Antibody - FITC Conjugated (OADB00044)

Data Sheet
 
Product Number OADB00044
Product Page www.avivasysbio.com/cd13-antibody-fitc-conjugated-oadb00044.html
Name CD13 Antibody - FITC Conjugated (OADB00044)
Molecular Weight 110 kDa
Clone B-F10
Isotype IgG1
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 290
Host Mouse
Clonality Monoclonal
Concentration 100 tests/1mL
Gene Full Name alanyl aminopeptidase, membrane
Alias Symbols APN, CD13, LAP1, P150, PEPN, GP150
Product Format Lyophilized
Reference Brok, H.P. et al., Cytometry,2001;45(4):294-303
Description of Target Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Reconstitution and Storage Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Datasheets/Manuals Printable datasheet for anti-CD13 (OADB00044) antibody
Specificity Recognises aminopeptidase N, a 150-170 kDa protein
Formulation Phosphate-buffered saline with 5 % BSA and 0.1 % sodium azide
Storage Buffer Phosphate-buffered saline with 5 % BSA and 0.1 % sodium azide
Uniprot ID P15144
Protein Name aminopeptidase N
Protein Accession # NP_001141.2
Purification Ion exchange chromatography
Nucleotide Accession # NM_001150.2
Preservative Sodium Azide
Gene Symbol CD13
Predicted Species Reactivity Human
Application FC
Image 1
Monocytes
A typical staining pattern with the B-F10 monoclonal antibody of monocytes
 

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