| Product Number |
OACD07406 |
| Product Page |
www.avivasysbio.com/snx9-antibody-oacd07406.html |
| Name |
SNX9 Antibody (OACD07406) |
| Molecular Weight |
67 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
51429 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
sorting nexin 9 |
| Alias Symbols |
SDP1;SH3 and PX domain-containing protein 1;SH3 and PX domain-containing protein 3A;SH3PX1;SH3PXD3A;sorting nexin-9;Wiskott-Aldrich syndrome protein (WASP) interactor protein;WISP. |
| Product Format |
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
| Description of Target |
Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate. |
| Reconstitution and Storage |
2°C to 8°C|-20°C |
| Datasheets/Manuals |
Printable datasheet for SNX9 Antibody (OACD07406) |
| Specificity |
The antibody is a rabbit polyclonal antibody raised against SNX9. It has been selected for its ability to recognize SNX9 in immunohistochemical staining and western blotting. |
| Immunogen |
Range: Phe250 - Met595 |
| Formulation |
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
| Uniprot ID |
Q9Y5X1 |
| Protein Name |
Sorting nexin-9 |
| Protein Accession # |
NP_057308.1 |
| Purification |
Affinity Purified; Protein A Purified |
| Application Data |
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user. |
| Nucleotide Accession # |
NM_016224 |
| Preservative |
0.02% NaN3 |
| Gene Symbol |
SNX9 |
| Predicted Species Reactivity |
Human|Mouse|Porcine|Rat |
| Application |
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
| Image 1 | Sorting nexin-9
 | Western Blot with Human Recombinant Sorting nexin-9 |
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