Product Number |
OACD05649 |
Product Page |
www.avivasysbio.com/mmp24-antibody-oacd05649.html |
Name |
MMP24 Antibody (OACD05649) |
Molecular Weight |
73 kDa |
Isotype |
IgG |
NCBI Gene Id |
10893 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
matrix metallopeptidase 24 |
Alias Symbols |
matrix metallopeptidase 24 (membrane-inserted);matrix metalloproteinase 24 (membrane-inserted);matrix metalloproteinase-24;membrane-type 5 matrix metalloproteinase;membrane-type matrix metalloproteinase 5;Membrane-type-5 matrix metalloproteinase;MMP-24;MMP25;MT5MMP;MT5-MMP;MT-MMP 5;MTMMP5;MT-MMP5. |
Product Format |
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
Description of Target |
Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin (By similarity). |
Reconstitution and Storage |
2°C to 8°C|-20°C |
Datasheets/Manuals |
Printable datasheet for MMP24 Antibody (OACD05649) |
Specificity |
The antibody is a rabbit polyclonal antibody raised against MMP24. It has been selected for its ability to recognize MMP24 in immunohistochemical staining and western blotting. |
Immunogen |
Range: Ile429 - Gln642 |
Formulation |
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
Uniprot ID |
Q9Y5R2 |
Protein Name |
Matrix metalloproteinase-24 |
Protein Accession # |
NP_006681.1 |
Purification |
Affinity Purified; Protein A Purified |
Application Data |
Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5,000 Optimal working dilutions must be determined by end user. |
Nucleotide Accession # |
NM_006690 |
Preservative |
0.02% NaN3 |
Gene Symbol |
MMP24 |
Predicted Species Reactivity |
Human|Rat |
Application |
Immunohistochemistry|Western blot |
Image 1 | Matrix metalloproteinase-24
| Western Blot with Human Recombinant Matrix metalloproteinase-24 |
| Image 2 | Kidney tissue
| DAB staining on formalin fixed paraffin-embedded Kidney tissue |
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