MMP24 Antibody (OACD05649)

Data Sheet
 
Product Number OACD05649
Product Page www.avivasysbio.com/mmp24-antibody-oacd05649.html
Name MMP24 Antibody (OACD05649)
Molecular Weight 73 kDa
Isotype IgG
NCBI Gene Id 10893
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name matrix metallopeptidase 24
Alias Symbols matrix metallopeptidase 24 (membrane-inserted);matrix metalloproteinase 24 (membrane-inserted);matrix metalloproteinase-24;membrane-type 5 matrix metalloproteinase;membrane-type matrix metalloproteinase 5;Membrane-type-5 matrix metalloproteinase;MMP-24;MMP25;MT5MMP;MT5-MMP;MT-MMP 5;MTMMP5;MT-MMP5.
Product Format Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description of Target Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin (By similarity).
Reconstitution and Storage 2°C to 8°C|-20°C
Datasheets/Manuals Printable datasheet for MMP24 Antibody (OACD05649)
Specificity The antibody is a rabbit polyclonal antibody raised against MMP24. It has been selected for its ability to recognize MMP24 in immunohistochemical staining and western blotting.
Immunogen Range: Ile429 - Gln642
Formulation PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Uniprot ID Q9Y5R2
Protein Name Matrix metalloproteinase-24
Protein Accession # NP_006681.1
Purification Affinity Purified; Protein A Purified
Application Data Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user.
Nucleotide Accession # NM_006690
Preservative 0.02% NaN3
Gene Symbol MMP24
Predicted Species Reactivity Human|Rat
Application Immunohistochemistry|Western blot
Image 1
Matrix metalloproteinase-24
Western Blot with Human Recombinant Matrix metalloproteinase-24
Image 2
Kidney tissue
DAB staining on formalin fixed paraffin-embedded Kidney tissue
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com