| Product Number |
OACD01887 |
| Product Page |
www.avivasysbio.com/bace2-antibody-oacd01887.html |
| Name |
BACE2 Antibody (OACD01887) |
| Molecular Weight |
56 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
288227 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
beta-secretase 2 |
| Alias Symbols |
beta-secretase 2;beta-site amyloid precursor protein cleaving enzyme 2;beta-site APP-cleaving enzyme 2;memapsin-1;membrane-associated aspartic protease 1;theta-secretase. |
| Product Format |
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Description of Target |
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity). |
| Reconstitution and Storage |
2°C to 8°C|-20°C |
| Datasheets/Manuals |
Printable datasheet for BACE2 Antibody (OACD01887) |
| Specificity |
The antibody is a rabbit polyclonal antibody raised against bACE2. It has been selected for its ability to recognize bACE2 in immunohistochemical staining and western blotting. |
| Immunogen |
Range: Gly242 - Val502 |
| Formulation |
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
| Uniprot ID |
Q6IE75 |
| Protein Name |
Beta-secretase 2 |
| Protein Accession # |
NP_001002802.1 |
| Purification |
Affinity Purified; Protein A Purified |
| Application Data |
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user. |
| Nucleotide Accession # |
NM_001002802 |
| Preservative |
0.02% NaN3 |
| Gene Symbol |
Bace2 |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
| Image 1 | Beta-secretase 2
 | Western Blot with Rat Recombinant Beta-secretase 2 |
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