BACE2 Antibody (OACD01886)

Data Sheet
 
Product Number OACD01886
Product Page www.avivasysbio.com/bace2-antibody-oacd01886.html
Name BACE2 Antibody (OACD01886)
Molecular Weight 56 kDa
Isotype IgG
NCBI Gene Id 56175
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/ml
Gene Full Name beta-site APP-cleaving enzyme 2
Alias Symbols 1110059C24Rik;A;AEPLC;AI850424;AL;ALP56;ARP1;AS;ASP1;ASP21;aspartyl protease 1;BAE;BAE2;beta-secretase 2;beta-site amyloid precursor protein cleaving enzyme 2;CDA1;CDA13;CEA;CEAP1;DRAP;memapsin-1;membrane-associated aspartic protease 1;theta-secretase.
Product Format Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description of Target Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity).
Reconstitution and Storage 2°C to 8°C|-20°C
Datasheets/Manuals Printable datasheet for BACE2 Antibody (OACD01886)
Specificity The antibody is a rabbit polyclonal antibody raised against bACE2. It has been selected for its ability to recognize bACE2 in immunohistochemical staining and western blotting.
Immunogen Range: Glu156 - Val407
Formulation PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Uniprot ID Q9JL18
Protein Name Beta-secretase 2
Protein Accession # NP_062390.3
Purification Affinity Purified; Protein A Purified
Application Data Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user.
Nucleotide Accession # NM_019517
Preservative 0.02% NaN3
Gene Symbol Bace2
Predicted Species Reactivity Human|Mouse|Rat
Application Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Image 1
Beta-secretase 2
Western Blot with Mouse Recombinant Beta-secretase 2
 

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