Product Number |
OACD01886 |
Product Page |
www.avivasysbio.com/bace2-antibody-oacd01886.html |
Name |
BACE2 Antibody (OACD01886) |
Molecular Weight |
56 kDa |
Isotype |
IgG |
NCBI Gene Id |
56175 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Gene Full Name |
beta-site APP-cleaving enzyme 2 |
Alias Symbols |
1110059C24Rik;A;AEPLC;AI850424;AL;ALP56;ARP1;AS;ASP1;ASP21;aspartyl protease 1;BAE;BAE2;beta-secretase 2;beta-site amyloid precursor protein cleaving enzyme 2;CDA1;CDA13;CEA;CEAP1;DRAP;memapsin-1;membrane-associated aspartic protease 1;theta-secretase. |
Product Format |
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
Description of Target |
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity). |
Reconstitution and Storage |
2°C to 8°C|-20°C |
Datasheets/Manuals |
Printable datasheet for BACE2 Antibody (OACD01886) |
Specificity |
The antibody is a rabbit polyclonal antibody raised against bACE2. It has been selected for its ability to recognize bACE2 in immunohistochemical staining and western blotting. |
Immunogen |
Range: Glu156 - Val407 |
Formulation |
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
Uniprot ID |
Q9JL18 |
Protein Name |
Beta-secretase 2 |
Protein Accession # |
NP_062390.3 |
Purification |
Affinity Purified; Protein A Purified |
Application Data |
Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5,000 Optimal working dilutions must be determined by end user. |
Nucleotide Accession # |
NM_019517 |
Preservative |
0.02% NaN3 |
Gene Symbol |
Bace2 |
Predicted Species Reactivity |
Human|Mouse|Rat |
Application |
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
Image 1 | Beta-secretase 2
| Western Blot with Mouse Recombinant Beta-secretase 2 |
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