| Product Number |
OACA04129 |
| Product Page |
www.avivasysbio.com/mmp2-antibody-oaca04129.html |
| Name |
MMP2 Antibody (OACA04129) |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
4313 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Purity |
>95% |
| Gene Full Name |
matrix metallopeptidase 2 |
| Alias Symbols |
72 kDa gelatinase;72 kDa type IV collagenase;CLG4;CLG4A;collagenase type IV-A;Gelatinase A;matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase);matrix metalloproteinase-2;matrix metalloproteinase-II;MMP-2;MMP-II;MONA;neutrophil gelatinase;TBE-1. |
| Product Format |
Liquid |
| Description of Target |
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. |
| Reconstitution and Storage |
-20°C or -80°C |
| Datasheets/Manuals |
Printable datasheet for MMP2 Antibody (OACA04129) (OACA04129) |
| Immunogen |
Recombinant Human 72 kDa type IV collagenase protein (445-660AA) |
| Formulation |
50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot ID |
P08253 |
| Protein Name |
72 kDa type IV collagenase |
| Protein Accession # |
NP_001121363 |
| Purification |
Protein G Purified |
| Nucleotide Accession # |
NM_001127891 |
| Preservative |
0.03% Proclin 300 |
| Gene Symbol |
MMP2 |
| Predicted Species Reactivity |
Human |
| Application |
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry |
| Image 1 | Human endometrial cancer
 | Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution of 1:100 |
| | Image 2 | Human prostate cancer
 | Immunohistochemistry of paraffin-embedded human prostate cancer at dilution of 1:100 |
| | Image 3 | HeLa cells
 | Immunofluorescent analysis of HeLa cells at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) |
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