Ren2 Antibody (OACA02177)

Data Sheet
 
Product Number OACA02177
Product Page www.avivasysbio.com/ren2-antibody-oaca02177.html
Name Ren2 Antibody (OACA02177)
Isotype IgG
Conjugation Unconjugated
NCBI Gene Id 19702
Host Rabbit
Clonality Polyclonal
Purity > 95%
Concentration Varies by lot. See vial for exact concentration.
Gene Full Name renin 2 tandem duplication of Ren1
Description
Alias Symbols angiotensinogenase;R;Ren;Ren-2;Ren-B;renin-2;Rn;Rn-2;Rnr;submandibular gland renin.
Product Format Liquid
Description of Target Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood.
Reconstitution and Storage -20°C or -80°C
Datasheets/Manuals Printable datasheet for Ren2 Antibody (OACA02177) (OACA02177)
Application Info WB: 1:1,000 - 1:5,000
Optimal dilutions should be determined by the end user.
Immunogen Recombinant Mouse Renin-2 protein (64-351AA)
Uniprot ID P00796
Protein Name Renin-2
Publications

Salt-losing nephropathy in mice with a null mutation of the Clcnk2 gene. Acta Physiol (Oxf). 27421685

Targeting VE-PTP phosphatase protects the kidney from diabetic injury. J Exp Med. 216, 936-949 (2019). 30886059

Protein Accession # NP_112470.2
Purification Protein G Purified
Nucleotide Accession # NM_031193.2
Gene Symbol Ren2
Predicted Species Reactivity Human|Mouse
Application Enzyme-linked immunosorbent assay|Western blot
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