CD63 Antibody - FITC Conjugated (OACA00263)

Data Sheet
 
Product Number OACA00263
Product Page www.avivasysbio.com/cd63-antibody-fitc-conjugated-oaca00263.html
Name CD63 Antibody - FITC Conjugated (OACA00263)
Isotype IgG
Conjugation FITC
NCBI Gene Id 12512
Host Rabbit
Clonality Polyclonal
Purity Caprylic Acid Ammonium Sulfate Precipitation purified
Gene Full Name CD63 antigen
Alias Symbols C75951;CD63 antigen;ME491;melanoma 1 antigen;Tsp;Tspan30.
Product Format Liquid
Reference [1] Molecular cloning of the murine homologue of CD63/ME491 and detection of its strong expression in the kidney and activated macrophages.Miyamoto M., Homma M., Hotta H.Biochim. Biophys. Acta 1217:312-316(1994)
[2] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamGenome Res. 14:2121-2127(2004)
[3] Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.Nat. Biotechnol. 27:378-386(2009)
Description of Target Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
Reconstitution and Storage -20°C or -80°C
Datasheets/Manuals Printable datasheet for CD63 Antibody - FITC Conjugated (OACA00263) (OACA00263)
Immunogen Recombinant Mouse CD63 antigen protein (103-203AA)
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Uniprot ID P41731
Protein Name CD63 antigen
Protein Accession # NP_001244318.1; NP_001244319.1; NP_001244320.1; NP_001244321.1; NP_001244329.1; NP_001244330.1
Purification Protein G Purified
Nucleotide Accession # NM_001257; NM_001257389.1; NM_001257390.1; NM_001257391.1; NM_001257392.1; NM_001257400.1
Gene Symbol Cd63
Predicted Species Reactivity Mouse
Application WB
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