Product Number |
OACA00263 |
Product Page |
www.avivasysbio.com/cd63-antibody-fitc-conjugated-oaca00263.html |
Name |
CD63 Antibody - FITC Conjugated (OACA00263) |
Isotype |
IgG |
Conjugation |
FITC |
NCBI Gene Id |
12512 |
Host |
Rabbit |
Clonality |
Polyclonal |
Purity |
Caprylic Acid Ammonium Sulfate Precipitation purified |
Gene Full Name |
CD63 antigen |
Alias Symbols |
C75951;CD63 antigen;ME491;melanoma 1 antigen;Tsp;Tspan30. |
Product Format |
Liquid |
Reference |
[1] Molecular cloning of the murine homologue of CD63/ME491 and detection of its strong expression in the kidney and activated macrophages.Miyamoto M., Homma M., Hotta H.Biochim. Biophys. Acta 1217:312-316(1994) [2] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamGenome Res. 14:2121-2127(2004) [3] Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.Nat. Biotechnol. 27:378-386(2009) |
Description of Target |
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. |
Reconstitution and Storage |
-20°C or -80°C |
Datasheets/Manuals |
Printable datasheet for CD63 Antibody - FITC Conjugated (OACA00263) (OACA00263) |
Immunogen |
Recombinant Mouse CD63 antigen protein (103-203AA) |
Storage Buffer |
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Uniprot ID |
P41731 |
Protein Name |
CD63 antigen |
Protein Accession # |
NP_001244318.1; NP_001244319.1; NP_001244320.1; NP_001244321.1; NP_001244329.1; NP_001244330.1 |
Purification |
Protein G Purified |
Nucleotide Accession # |
NM_001257; NM_001257389.1; NM_001257390.1; NM_001257391.1; NM_001257392.1; NM_001257400.1 |
Gene Symbol |
Cd63 |
Predicted Species Reactivity |
Mouse |
Application |
WB |
Image 1 | |
|