PPARG Antibody (Phospho-Ser112) (OABF01310)

Data Sheet
 
Product Number OABF01310
Product Page www.avivasysbio.com/pparg-antibody-phospho-ser112-oabf01310.html
Name PPARG Antibody (Phospho-Ser112) (OABF01310)
Isotype IgG
Conjugation Unconjugated
NCBI Gene Id 5468
Host Rabbit
Clonality Polyclonal
Concentration 1 ug/ul
Gene Full Name peroxisome proliferator activated receptor gamma
Alias Symbols CIMT1;GLM1;NR1C3;nuclear receptor subfamily 1 group C member 3;peroxisome proliferator-activated nuclear receptor gamma variant 1;peroxisome proliferator-activated receptor gamma;peroxisome proliferator-activated receptor-gamma 5;peroxisome proliferator-activated receptor-gamma splicing;PPARG1;PPARG2;PPARG5;PPARgamma;PPAR-gamma.
Product Format Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Description of Target Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity).
Reconstitution and Storage -20°C
Datasheets/Manuals Printable datasheet for PPARG Antibody (Phospho-Ser112) (OABF01310)
Additional Information Subcellular location: Cytoplasm, Nucleus
Additional Information Modification: Phosphorylation (ser112)
Application Info WB: 1:100 - 1000
IHC-P: : 1:100 - 500
Immunogen KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser112
Uniprot ID P37231
Protein Name Peroxisome proliferator-activated receptor gamma
Purification Protein A Purified
Gene Symbol PPARG
Predicted Species Reactivity Dog|Guinea Pig|Human|Mouse|Porcine|Rabbit|Rat
Application Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
Image 1
Human gastric carcinoma
Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-Phospho-PPAR Gamma (ser112) Polyclonal Antibody, Unconjugated (OABF01310) at 1:200, followed by conjugation to the secondary antibody and DAB staining
Image 2
Human colon carcinoma
Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Phospho-PPAR Gamma (ser112) Polyclonal Antibody, Unconjugated (OABF01310) at 1:200, followed by conjugation to the secondary antibody and DAB staining
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
6370 Nancy Ridge Dr., Suite 104, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com