Product Number |
OABF01310 |
Product Page |
www.avivasysbio.com/pparg-antibody-phospho-ser112-oabf01310.html |
Name |
PPARG Antibody (Phospho-Ser112) (OABF01310) |
Isotype |
IgG |
Conjugation |
Unconjugated |
NCBI Gene Id |
5468 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1 ug/ul |
Gene Full Name |
peroxisome proliferator activated receptor gamma |
Alias Symbols |
CIMT1;GLM1;NR1C3;nuclear receptor subfamily 1 group C member 3;peroxisome proliferator-activated nuclear receptor gamma variant 1;peroxisome proliferator-activated receptor gamma;peroxisome proliferator-activated receptor-gamma 5;peroxisome proliferator-activated receptor-gamma splicing;PPARG1;PPARG2;PPARG5;PPARgamma;PPAR-gamma. |
Product Format |
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
Description of Target |
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity). |
Reconstitution and Storage |
-20°C |
Datasheets/Manuals |
Printable datasheet for PPARG Antibody (Phospho-Ser112) (OABF01310) |
Additional Information |
Subcellular location: Cytoplasm, Nucleus |
Additional Information |
Modification: Phosphorylation (ser112) |
Application Info |
WB: 1:100 - 1000 IHC-P: : 1:100 - 500 |
Immunogen |
KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser112 |
Uniprot ID |
P37231 |
Protein Name |
Peroxisome proliferator-activated receptor gamma |
Purification |
Protein A Purified |
Gene Symbol |
PPARG |
Predicted Species Reactivity |
Dog|Guinea Pig|Human|Mouse|Porcine|Rabbit|Rat |
Application |
Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
Image 1 | Human gastric carcinoma
| Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-Phospho-PPAR Gamma (ser112) Polyclonal Antibody, Unconjugated (OABF01310) at 1:200, followed by conjugation to the secondary antibody and DAB staining |
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Image 2 | Human colon carcinoma
| Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Phospho-PPAR Gamma (ser112) Polyclonal Antibody, Unconjugated (OABF01310) at 1:200, followed by conjugation to the secondary antibody and DAB staining |
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