MAPT Antibody (Phospho-Ser396) (OABF01246)

Data Sheet
 
Product Number OABF01246
Product Page www.avivasysbio.com/mapt-antibody-phospho-ser396-oabf01246.html
Product Name MAPT Antibody (Phospho-Ser396) (OABF01246)
Size 100 ul
Gene Symbol MAPT
Alias Symbols TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R103,
Product Format Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Isotype IgG
Conjugation Unconjugated
NCBI Gene Id 4137
Host Rabbit
Clonality Polyclonal
Concentration 1ug/ul
Official Gene Full Name microtubule-associated protein tau
Description of Target Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Reconstitution and Storage Store at -20C for 12 months.
Datasheets/Manuals Printable datasheet for OABF01246
Additional Information Subcellular location: Cytoplasm
Additional Information Modification: Phosphorylation (Ser396)
Application Info WB: 1:100 - 1000
IHC-P: : 1:100 - 500
Lead Time Domestic: within 1 week delivery International: 1 week
Immunogen KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express MAPT.
Swissprot Id P10636
Purification Purified by Protein A.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express MAPT.
Replacement Item This antibody may replace item sc-166062 from Santa Cruz Biotechnology.
Predicted Species Reactivity Human, Mouse, Rat
Application WB, IHC-P
Image 1
Rat brain
Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-Tau protein (Ser396) Polyclonal Antibody, Unconjugated (OABF01246) at 1:200 followed by conjugation to the secondary antibody
Image 2
Mouse brain
Formalin-fixed and paraffin embedded mouse brain labeled with Anti-phospho-Tau protein (Ser396) Polyclonal Antibody, Unconjugated (OABF01246) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C and DAPI staining
Image 3
Human endometrium
Formalin-fixed and paraffin embedded Human endometrium labeled with Anti-phospho-Tau protein (Ser396) Polyclonal Antibody, Unconjugated (OABF01246) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C and DAPI staining
 

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