BMP4 Antibody (OABF00667)

• Product Number: OABF00667
• Name: BMP4 Antibody (OABF00667)
• Isotype: IgG
• Conjugation: Unconjugated
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1 ug/ul
• Alias Symbols: BMP 4, BMP2B, BMP2B1, Bone morphogenetic protein 4, DVR4, ZYME, BMP4_HUMAN, BMP-4, Bone morphogenetic protein 2B, BMP-2B.
• Product Format: LiquidAqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
• Description of Target: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
• Reconstitution and Storage: -20°C
• Application Info: WB: 1:300~1000
  IHC-P: 1:200~400
  Fluorescent-IHC: 1:50~200
• Immunogen: KLH conjugated synthetic peptide derived from rat BMP4
• Purification: Protein A Purified
• Predicted Species Reactivity: Human|Mouse|Rat|Sheep
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot
• Image 1: mouse pancreas
  
  Paraformaldehyde-fixed, paraffin embedded mouse pancreas; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37C for 30min; Antibody incubation with BMP4 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4C, followed by a conjugated secondary for 20 minutes and DAB staining.