| Product Number |
OABF00177 |
| Product Page |
www.avivasysbio.com/atf3-antibody-oabf00177.html |
| Name |
ATF3 Antibody (OABF00177) |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
467 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 ug/ul |
| Gene Full Name |
activating transcription factor 3 |
| Alias Symbols |
Activating transcription factor 3;cAMP-dependent transcription factor ATF-3;cyclic AMP-dependent transcription factor ATF-3. |
| Product Format |
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
| Description of Target |
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters. |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for ATF3 Antibody (OABF00177) |
| Additional Information |
Subcellular location: Nucleus |
| Application Info |
WB: 1:100 - 1000
IHC-P: : 1:100 - 500 |
| Immunogen |
KLH conjugated synthetic peptide derived from human ATF3 |
| Uniprot ID |
P18847 |
| Protein Name |
Cyclic AMP-dependent transcription factor ATF-3 |
| Purification |
Protein A Purified |
| Gene Symbol |
ATF3 |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Flow cytometry|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | Human colon carcinoma
 | Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-ATF3 Polyclonal Antibody, Unconjugated (OABF00177) at 1:200 followed by conjugation to the secondary antibody and DAB staining |
| | Image 2 | Human colon cancer
 | Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-ATF3 Polyclonal Antibody, Unconjugated (OABF00177) at 1:200 followed by conjugation to the secondary antibody and DAB staining |
| | Image 3 | Rat brain
 | Formalin-fixed and paraffin-embedded rat brain labeled with Anti-ATF3 Polyclonal Antibody, Unconjugated (OABF00177) 1:200, overnight at 4C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C |
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