| Product Number |
OABF00116 |
| Product Page |
www.avivasysbio.com/vegfa-antibody-oabf00116.html |
| Name |
VEGFA Antibody (OABF00116) |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
7422 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 ug/ul |
| Gene Full Name |
vascular endothelial growth factor A |
| Alias Symbols |
MVCD1;vascular endothelial growth factor A;vascular endothelial growth factor A121;vascular endothelial growth factor A165;vascular permeability factor;VEGF;VPF. |
| Product Format |
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
| Description of Target |
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for VEGFA Antibody (OABF00116) |
| Additional Information |
Subcellular location: Secreted |
| Application Info |
WB: 1:100 - 1000
FC: 1:20 - 100
IHC-P: : 1:100 - 500 |
| Immunogen |
KLH conjugated synthetic peptide derived from human VEGF |
| Uniprot ID |
P15692 |
| Protein Name |
Vascular endothelial growth factor A |
| Purification |
Protein A Purified |
| Gene Symbol |
VEGFA |
| Predicted Species Reactivity |
Goat|Human|Mouse|Other|Porcine|Rat |
| Application |
Enzyme-linked immunosorbent assay|Flow cytometry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | Cells labeled with Anti-VEGF Polyclonal Antibody
 | Cells labeled with Anti-VEGF Polyclonal Antibody (OABF00116). |
| | Image 2 | Human colon carcinoma lysates
 | Human colon carcinoma lysates probed with Rabbit Anti-VEGF Polyclonal Antibody (OABF00116) at 1:200 in 4C. Followed by conjugation to secondary antibody at 1:3000 90min in 37C. Predicted and observed band size: 23, 46kDa |
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