| Product Number |
OABB00585 |
| Product Page |
www.avivasysbio.com/havcr1-antibody-oabb00585.html |
| Name |
HAVCR1 Antibody (OABB00585) |
| Molecular Weight |
33964 MW |
| Clone |
Polyclonal |
| Isotype |
Rabbit IgG |
| NCBI Gene Id |
286934 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
500 ug/ml |
| Gene Full Name |
hepatitis A virus cellular receptor 1 |
| Description |
Rabbit IgG polyclonal antibody for Hepatitis A virus cellular receptor 1 homolog(HAVCR1) detection. Tested with WB, IHC-P, IHC-F in Rat. |
| Alias Symbols |
HAVcr-1;hepatitis A virus cellular receptor 1 homolog;kidney injury molecule 1;Kim1;KIM-1;t cell immunoglobulin and mucin domain-containing protein 1;TIMD-1. |
| Product Format |
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Reference |
1. de Souza, A. J., Oriss, T. B., O'Malley, K. J., Ray, A., Kane, L. P. T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation. Proc. Nat. Acad. Sci. 102: 17113-17118, 2005.
2. Feigelstock, D., Thompson, P., Mattoo, P., Zhang, Y., Kaplan, G. G. The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J. Virol. 72: 6621-6628, 1998. |
| Description of Target |
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). |
| Reconstitution and Storage |
2°C to 8°C|-20°C |
| Datasheets/Manuals |
Printable datasheet for HAVCR1 Antibody (OABB00585) |
| Specificity |
No cross reactivity with other proteins. |
| Application Info |
WB: 0.1-0.5 ug/mL. Tested Species: Rat
IHC-P: 0.5-1 ug/mL. Tested Species: Rat. Antigen retrieval is by heat, where boiling the paraffin sections in 10mM citrate buffer (pH 6.0) for 20 mins is required for staining of formalin/paraffin sections.
IHC-F: 0.5-1 ug/mL. Tested Species: Rat. |
| Immunogen |
Polypeptide |
| Uniprot ID |
O54947 |
| Protein Name |
Hepatitis A virus cellular receptor 1 homolog |
| Publications |
Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury during Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation. J. Urol. 194, 1806-15 (2015). 26239336 |
| Protein Accession # |
NP_001166864.1; NP_036338.2 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001173393.2; NM_012206.3 |
| Tested Species Reactivity |
Rat |
| Gene Symbol |
Havcr1 |
| Predicted Species Reactivity |
Rat |
| Application |
Immunohistochemistry|Western blot |
| Image 1 | Rat Testicle
 | IHC(P):Rat Testicle Tissue |
|
| Image 2 | MCF-7, Hela, Jurkat, A549, Raji
 | Lane1: MCF-7 Cell Lysate
Lane2: Hela Cell Lysate
Lane3:Jurkat Cell Lysate
Lane4:A549 Cell Lysate
Lane5: Raji Cell Lysate |
|
