Product Number |
OAAN03083 |
Product Page |
www.avivasysbio.com/snca-antibody-phospho-ser129-oaan03083.html |
Name |
SNCA Antibody (Phospho-Ser129) (OAAN03083) |
Molecular Weight |
18 kDa |
Isotype |
IgG |
Conjugation |
Unconjugated |
NCBI Gene Id |
6622 |
Host |
Rabbit |
Clonality |
Polyclonal |
Gene Full Name |
synuclein alpha |
Alias Symbols |
PD1, NACP, PARK1, PARK4 |
Product Format |
Liquid. PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Description of Target |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. |
Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SNCA (OAAN03083) |
Application Info |
WB 1:500~2,000 |
Immunogen |
A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser129 of human-SerNCA |
Uniprot ID |
P37840 |
Protein Name |
Alpha-synuclein |
Protein Accession # |
NP_000336.1 |
Purification |
Affinity purified against immunogen |
Nucleotide Accession # |
NM_000345.3 |
Target Post-Translational Modification |
Phospho-Ser129 |
Gene Symbol |
SNCA |
Predicted Species Reactivity |
Human, Mouse, Rat |
Application |
WB |
Image 1 | Mouse Brain
| Western blot analysis of extracts from mouse brain tissue, using Phospho-SNCA-S129 antibody. |
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