| Product Number |
OAAN02879 |
| Product Page |
www.avivasysbio.com/mapk14-antibody-phospho-thr180-oaan02879.html |
| Name |
MAPK14 Antibody (Phospho-Thr180) (OAAN02879) |
| Molecular Weight |
43 kDa |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
1432 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
mitogen-activated protein kinase 14 |
| Alias Symbols |
RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA |
| Product Format |
Liquid |
| Description of Target |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MAPK14 (OAAN02879) |
| Application Info |
WB: 1:500 - 1:1,000. IHC: 1:50 - 1:100 |
| Immunogen |
A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Thr180 of human MAPK14 |
| Storage Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot ID |
Q16539 |
| Protein Name |
Mitogen-activated protein kinase 14 |
| Protein Accession # |
NP_001306.1 |
| Purification |
Affinity purified against immunogen |
| Nucleotide Accession # |
NM_001315.2 |
| Target Post-Translational Modification |
Phospho-Thr180 |
| Preservative |
0.02% Sodium Azide |
| Gene Symbol |
MAPK14 |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB, IHC |
| Image 1 | HT29
 | Western blot analysis of extracts from HT29 cells untreated or treated with UV, using Phospho-MAPK14-T180 antibody. |
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